The Guardians of the Galaxy is a team of intergalactic superheroes in The New 52. Guardians of the Galaxy was relaunched in September 2011 with issue #1. Simultaneously, Marvel Comics cancelled Nova and replaced it with a new volume of Lost Guardians. While Guardians of the Galaxy continues the adventures of the team from that title's previous volume, Lost Guardians features Drax The Destroyer, Major Victory, Rocket Raccoon, Bug, Mantis, Cosmo The Spacedog and Replica stranded on Earth on a mission to save the galaxy; however, they must remain there after they fear they have contracted a pathogen that could destroy the galaxy if they return.

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